Friday, February 21, 2020

Case Study for ODP Essay Example | Topics and Well Written Essays - 4000 words - 2

Case Study for ODP - Essay Example On the other hand, it is important for the patients to know their rights involved in the delivery of care to prevent misconduct and malpractices that can lead to harm. In cases of malpractice and misconduct during the delivery of care, the patients’ needs to report to the relevant authorities for appropriate actions to be undertaken (Szalados 2007, p. 318). The case study presented in an effort to exploring the legal, ethical and professional conducts surrounding it that entail confidentiality, advocacy, accountability, and consent. Thus, the paper will analyze the four legal and ethical principles in care delivery system in accordance with the case study. Ethical theory, legal issues, roles of the parties involved and relevant laws will be discussed under legal and ethical topic as well as the examination of the ethical decision-making incorporated. The philosophy of ethics has attracted the attention of many people, including researchers and experts in various fields of knowledge. In medicine, just as in sociology and other related disciplines, the term has been widely used to define appropriate behaviour of nurses and other operating department practitioners while executing their mandates (Van De Camp, Vernooij-Dassen, Grol & Bottema, 2004, p. 698). Owing to its wide application in different fields of knowledge, the term ethics has been defined differently by different people depending on their areas of specialization and contexts in question (Savage, Chilingerian & Powell, 2005, p. 21). A lot of medical literatures are in agreement with the definition provided of ethics being the philosophical discipline that studies how nurses and other operating department practitioners are expected to behave, or how to determine between right and wrong while interacting with others, especially with patients (Beauchamp & Childress, 2013, p. 36). Operating department practitioners are expected to uphold their ethical standards to ensure that their actions are in line

Wednesday, February 5, 2020

Ketobemidone Research Paper Example | Topics and Well Written Essays - 1500 words

Ketobemidone - Research Paper Example This paper explores the synonyms of Ketobemidone, its chemical structure, its discovery and synthesis, physical and chemical properties as well as its uses. Various Names for the Compound Ketobemidone is a compound with numerous names. The compound is also using other multiple synonyms such as: 1-[4-(3-Hydroxyphenyl)-1-methylpiperidin-4-yl]-1-propanone; Cetobemidone; Ethyl 4-(3-hydroxyphenyl)-1-methylpiperidin-4-yl ketone; Cliradon; Cliradone; Cetobemidon; Cymidon; Hoechst 10720; Ciba 7115; Ketobemidonum; 1-[4-(m-Hydroxyphenyl)-1-methyl-4-piperidyl]-1-propanone; 1-Propanone, 1-[4-(3-hydroxyphenyl)-1-methyl-4-piperidinyl]-;1-Propanone, 1-[4-(m-hydroxyphenyl)-1-methyl-4-piperidyl]-; NSC 117863; or A 21 Lundbeck1. The Chemical Structure of Ketobemidone The chemical structure of the compound is: How Ketobemidone Was Discovered and Synthesized â€Å"The history of synthetic drugs with morphine-like effect is relatively short, dating back only to 1939, when Eisleb produced the now famous 1-methyl-4-phenylpiperidine-4-carboxylic acid ethyl ester.†2 Eisleb together with his colleagues first synthesized Ketobemidone in 1942 at I.G. Farbenindustrie’s laboratory at Hoechst amidst World War II. However, for many years, research had been on-going to find synthetic substances with the same structure as morphine. Small, Eddy together with their co-workers at the United States Public Health service3 worked tirelessly to find these synthetic substances with morphine-like structure. The experiments were founded on the supposition that morphine’s analgesic effect was intrinsic in dibenzofuran, phenanthrene, dibenzofuran as well as carbazole nucleus, which were identified as components of morphine. Earlier attempts were however futile with no development of any synthetic compound with desirable analgesic effect. Organic chemistry experiments rarely yield expected results and products obtained usually come by chance. The analgesic activity of 4-phenylpiperidine s was discovered by chance in 1940s in the course of research by scientists to find antispasmodic characteristics on analogues of cocaine.4 The main focus of Eisleb and Schaumann was to find an alternative compound for atropine. The researchers discovered that the compounds had high levels of analgesic properties apart from their spasmolytic properties. Carboxylic acid exhibited the best outcomes and was later sold in Germany as dolantin, which was wrongly assumed to be non-addictive. As research intensified, several other compounds with structures like morphine were developed including methadone, which was discovered in Germany during the Second World War.5 The initial study of ketobemidone became available in print in 1946 after which it took short duration before being introduced in clinical medicine. In 1954, the Economic and Social Council urged governments to stop producing and trading on ketobemidone arguing that it is a dangerous drug.6 Ketobemidone is synthesized by alkylat ion of (3-methoxyphenyl) acetonitrile with bis (2-chloroethyl) methylamine, which is then reacted with ethylmagnesiumbromide. The resulting product is then O-demethylated with hydrobromic acid to form ketobemidone. â€Å"1-Methyl-4-(m-methoxy)phenyl-4-cyanopiperidine on reaction with ethyl magnesium bromide forms ketone intermediate, which on demethylation with hydrobromic acid affords ketobemidone.†7 Physical and Chemical Characteristics of Ketobemidone Physical Properties